Prothrombin complex concentrate
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198 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemophilia b | D002836 | — | D67 | 26 | 22 | 41 | 12 | 30 | 115 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | 23 | 20 | 39 | 7 | 25 | 100 |
| Hemorrhage | D006470 | MP_0001914 | R58 | 1 | 4 | 6 | 6 | 15 | 32 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | 2 | 1 | 7 | 1 | 4 | 15 |
| Hemostatic disorders | D020141 | — | — | 2 | 1 | 5 | 2 | 3 | 13 |
| Intracranial hemorrhages | D020300 | EFO_0000551 | I62 | 1 | — | — | 2 | 3 | 6 |
| Thrombosis | D013927 | — | — | 2 | 1 | — | 1 | 1 | 5 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 2 | 2 | 1 | — | 5 |
| Wounds and injuries | D014947 | — | T14.8 | — | 1 | 2 | 1 | 1 | 5 |
| Cerebral hemorrhage | D002543 | — | — | — | — | — | 2 | 2 | 4 |
Show 21 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | — | 3 | — | 2 | 5 |
| Coagulation protein disorders | D020147 | — | — | — | — | 2 | — | 2 | 4 |
| Hemorrhagic disorders | D006474 | — | D69.9 | — | — | 2 | — | 1 | 3 |
| Inborn genetic diseases | D030342 | EFO_0000508 | — | — | — | 1 | — | 1 | 2 |
| Hemorrhagic shock | D012771 | — | — | — | 1 | 1 | — | — | 2 |
| Thrombocytopenia | D013921 | HP_0001873 | D69.6 | — | — | 1 | — | — | 1 |
| X-linked genetic diseases | D040181 | — | — | — | — | 1 | — | — | 1 |
| Inherited blood coagulation disorders | D025861 | — | — | — | — | 1 | — | — | 1 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | 1 | — | — | 1 |
| Traumatic brain injuries | D000070642 | — | S06 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 6 | 1 | — | — | — | 6 |
| Transfusion reaction | D065227 | — | D69.51 | — | 1 | — | — | 1 | 2 |
| Thromboembolism | D013923 | — | — | — | 1 | — | — | 1 | 2 |
| Hip fractures | D006620 | EFO_0003964 | S72.00 | — | 1 | — | — | 1 | 2 |
| Bone fractures | D050723 | EFO_0003931 | T14.8 | — | 1 | — | — | 1 | 2 |
| Blood transfusion | D001803 | — | — | — | 1 | — | — | — | 1 |
| Postoperative complications | D011183 | — | — | — | 1 | — | — | — | 1 |
| Congenital heart defects | D006330 | — | Q24.9 | — | 1 | — | — | — | 1 |
| Acute lung injury | D055371 | EFO_0004610 | — | — | 1 | — | — | — | 1 |
| Lung injury | D055370 | — | S27.30 | — | 1 | — | — | — | 1 |
Show 5 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | 1 | — | — | — | — | 1 |
| Factor vii deficiency | D005168 | — | D68.2 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | — | — | 2 | 2 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | — | — | 1 | 1 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | — | 1 | 1 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | — | — | 1 | 1 |
| Central nervous system diseases | D002493 | — | G96.9 | — | — | — | — | 1 | 1 |
| Brain diseases | D001927 | — | G93.40 | — | — | — | — | 1 | 1 |
| Nervous system diseases | D009422 | — | G00-G99 | — | — | — | — | 1 | 1 |
| Lung transplantation | D016040 | — | — | — | — | — | — | 1 | 1 |
| Primary graft dysfunction | D055031 | — | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | — |
| INN | — |
| Description | — |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | — |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
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703 adverse events reported
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