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Drug ReportsProthrombin complex concentrate
Prothrombin complex concentrate
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
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Commercial
No data
Clinical
Clinical Trials
190 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hemophilia aD006467EFO_0007267D662522451231119
Hemophilia bD002836—D67242239929107
HemorrhageD006470MP_0001914R5824681434
Blood coagulation disordersD001778EFO_0009314D68.91163314
Hemostatic disordersD020141——1163314
Intracranial hemorrhagesD020300EFO_0000551I621——236
Cerebral hemorrhageD002543—————224
ThrombosisD013927——11—1—3
StrokeD020521EFO_0000712I63.9—1—113
Surgical blood lossD016063—————112
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Heart diseasesD006331EFO_0003777I51.9—22——4
Wounds and injuriesD014947—T14.8—12—14
Hemorrhagic shockD012771———11——2
Coagulation protein disordersD020147————1—12
ThrombocytopeniaD013921HP_0001873D69.6——1——1
Hematologic diseasesD006402EFO_0005803D75.9——1——1
Hemorrhagic disordersD006474—D69.9——1——1
Heart failureD006333EFO_0003144I50——1——1
Traumatic brain injuriesD000070642—S06——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———61———6
Transfusion reactionD065227—D69.51—1——12
ThromboembolismD013923———1——12
Hip fracturesD006620EFO_0003964S72.00—1——12
Bone fracturesD050723EFO_0003931T14.8—1——12
Blood transfusionD001803———1———1
Postoperative complicationsD011183———1———1
Congenital heart defectsD006330—Q24.9—1———1
Acute lung injuryD055371EFO_0004610——1———1
Lung injuryD055370—S27.30—1———1
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Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypersensitivityD006967EFO_0003785T78.40————22
Cardiopulmonary bypassD002315——————11
HypertensionD006973EFO_0000537I10————11
Cardiovascular diseasesD002318EFO_0000319I98————11
Diabetes mellitusD003920EFO_0000400E08-E13————11
Vascular diseasesD014652EFO_0004264I77————11
Central nervous system diseasesD002493—G96.9————11
Brain diseasesD001927—G93.40————11
Nervous system diseasesD009422—G00-G99————11
Lung transplantationD016040——————11
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name—
INN—
Description
—
Classification
Unknown
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL ID—
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID—
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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490 adverse events reported
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